Lissencephaly

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The surface of the brain is unusually smooth for a fetus at 28 weeks’ gestation (the Sylvian fossa is shallow and there is no sign of the cingulate and precentral gyrus; the texture of the cortex is more irregular and echogenic than usual

Reference(s):Malinger G, Kidron D, Schreiber L, Ben-Sira L, Hoffmann C, Lev D, Lerman-Sagie T. Prenatal diagnosis of malformations of cortical development by dedicated neurosonography. Ultrasound Obstet Gynecol 2007;29(2):178–91. PubMed PMID: 17219377.