Page last updated January 2018

This is a FREE resource designed to support the medical profession in their care of women made possible by over 750 expert clinicians who are generously providing their contributions without any remuneration and by the publishers who have paid personally for the creation of this site in the memory of their daughter, Abigail.

Current Authors

WBC (White Blood Count)

The white blood cell count measures the number of white blood cells in one microliter of blood.

White blood cells are produced in bone marrow, lymph nodes, the spleen and thymus. They fight infection and foreign bodies and help distribute antibodies throughout the body. Unused, a white blood cell lives for two to three weeks, and then disintegrates.

May be Increased in the Presence of:

  • Infection
  • Hemorrhage
  • Trauma
  • Some malignancies
  • Exposure to toxic substances
  • Thyroid storm
  • Renal failure
  • Some drugs (quinine, adrenalin and others)
  • Chronic inflammatory disease
  • Stress reactions
  • Exercise
  • Heat
  • Cold
  • Anesthesia
  • Cigarette smoking

May be Decreased in the Presence of:

  • Viral infections
  • Bone Marrow Disease
  • Bone Marrow Depression, secondary to:
    • Analgesics
    • Antibiotics
    • Antihistamines
    • Anticonvulsants
    • Antiinflammatory drugs
    • Antithyroid drugs
    • Arsenic
    • Barbiturates
    • Chemotherapy
    • Diuretics
    • Heavy metal contamination
    • Radiation exposure

Special Considerations

  • Smokers typically have elevated hematocrits in response to chronic, low-grade carbon monoxide poisoning and other mild respiratory ailments. Because of the carbon monoxide binding, they may still be functionally anemic, even though their hematocrit levels look good.
  • Adaptation to high altitudes includes moderate elevation of hematocrit.
  • During the initial phases of an acute hemorrhage, the hematocrit generally doesn't change very much. Later, as extracellular fluid is mobilized and IV fluids are incorporated, there is a dilutional effect that will lead to a reduced hematocrit. This fall in hematocrit may take several hours to develop.

Normal Values*

  #/l

Men

5,000-10,000
Women 5,000-10,000
Pregnancy 6,000-16,000

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.

 

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300