Page last updated April 2020

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A/G Ratio

Serum proteins are primarily albumin (50–60%, produced by the liver), but also include globulins and other proteins. 

Serum proteins:

  • Maintain water balance in the blood through osmotic pressure
  • Transport blood components and nutritional elements
  • Help the immune system
  • Help with coagulation

Although albumin is made exclusively in the liver, globulins are produced in many sites throughout the body. Thus, whether total protein is normal, elevated, or low, a decrease in the albumin:globulin (A/G ratio) often indicates the presence of impaired liver function.

Normal Values*

Men/Women >1

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.