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Alkaline Phosphatase

Alkaline Phosphatase (ALP) is an enzyme found in:
  • Bone
  • Liver
  • Placenta
  • Kidney
  • Intestines

Elevations may be found in:

  • Any traumatic injury to any of these structures
  • Any disease affecting one of these structures
  • Cirrhosis (large increase)
  • Liver metastasis (large increase)
  • Liver abscess (large increase)
  • Obstructed bile duct (large increase)
  • Bone cancers (large increase)
  • Hepatitis (moderate increase)
  • Hepatitis (moderate increase)
  • Pancreatitis (moderate increase)
  • Infectious mononucleosis
  • Hyperparathyroidism

Decreased amounts may be found in:

  • Malnutrition
  • Hypothyroidism
  • Pernicious anemia
  • Vitamin C deficiency

Normal Values*

Men 20–70 U/L


20–150 U/L
Pregnancy 60–200 U/L

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another. Normal values can vary quite markedly with the laboratory method used. Consult your local lab.




Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington DC, 20372-5300, USA